Michael Speca, Linda E. Carlson, Eileen Goodey, et al. · 2000 · Psychosomatic Medicine · 1,082 citations
OBJECTIVE: The objective of this study was to assess the effects of participation in a mindfulness meditation-based stress reduction program on mood disturbance and symptoms of stress in cancer outpatients. METHODS: A randomized, wait-list controlled design was used. A convenience sample of eligible cancer patients enrolled after giving informed consent and were randomly assigned to either an immediate treatment condition or a wait-list control condition. Patients completed the Profile of Mood States and the Symptoms of Stress Inventory both before and after the intervention. The intervention consisted of a weekly meditation group lasting 1.5 hours for 7 weeks plus home meditation practice.
Elizabeth A. Hoge, Éric Bui, Luana M. Marques, et al. · 2013 · The Journal of Clinical Psychiatry · 510 citations
Article Abstract Objective: Mindfulness meditation has met increasing interest as a therapeutic strategy for anxiety disorders, but prior studies have been limited by methodological concerns, including a lack of an active comparison group. This is the first randomized, controlled trial comparing the manualized Mindfulness-Based Stress Reduction (MBSR) program with an active control for generalized anxiety disorder (GAD), a disorder characterized by chronic worry and physiologic hyperarousal symptoms. Method: Ninety-three individuals with DSM-IV-diagnosed GAD were randomly assigned to an 8-week group intervention with MBSR or to an attention control, Stress Management Education (SME), between
Joseph Wielgosz, Simon Benjamin Goldberg, Tammi R. A. Kral, et al. · 2018 · Annual Review of Clinical Psychology · 435 citations
Mindfulness meditation is increasingly incorporated into mental health interventions, and theoretical concepts associated with it have influenced basic research on psychopathology. Here, we review the current understanding of mindfulness meditation through the lens of clinical neuroscience, outlining the core capacities targeted by mindfulness meditation and mapping them onto cognitive and affective constructs of the Research Domain Criteria matrix proposed by the National Institute of Mental Health. We review efficacious applications of mindfulness meditation to specific domains of psychopathology including depression, anxiety, chronic pain, and substance abuse, as well as emerging efforts
Fadel Z. Zeidan, Katherine T. Martucci, Robert Kraft, et al. · 2013 · Social Cognitive and Affective Neuroscience · 196 citations
Anxiety is the cognitive state related to the inability to control emotional responses to perceived threats. Anxiety is inversely related to brain activity associated with the cognitive regulation of emotions. Mindfulness meditation has been found to regulate anxiety. However, the brain mechanisms involved in meditation-related anxiety relief are largely unknown. We employed pulsed arterial spin labeling MRI to compare the effects of distraction in the form of attending to the breath (ATB; before meditation training) to mindfulness meditation (after meditation training) on state anxiety across the same subjects. Fifteen healthy subjects, with no prior meditation experience, participated in 4
Elizabeth A. Hoge, E. Bui, Sophie A. Palitz, et al. · 2017 · Psychiatry research · 191 citations
Mindfulness-Based interventions have increased in popularity in psychiatry, but the impact of these treatments on disorder-relevant biomarkers would greatly enhance efficacy and mechanistic evidence. If Generalized Anxiety Disorder (GAD) is successfully treated, relevant biomarkers should change, supporting the impact of treatment and suggesting improved resilience to stress. Seventy adults with GAD were randomized to receive either Mindfulness-Based Stress Reduction (MBSR) or an attention control class; before and after, they underwent the Trier Social Stress Test (TSST). Area-Under-the-Curve (AUC) concentrations were calculated for adrenocorticotropic hormone (ACTH) and pro-inflammatory cy
Peter la Cour, Marian Petersen · 2014 · Pain Medicine · 164 citations
OBJECTIVE: This randomized controlled clinical trial investigated the effects of mindfulness meditation on chronic pain. DESIGN: A total of 109 patients with nonspecific chronic pain were randomized to either a standardized mindfulness meditation program (mindfulness-based stress reduction [MBSR]) or to a wait list control. METHODS: Pain, physical function, mental function, pain acceptance, and health-related quality of life were measured. The SF36 vitality scale was chosen as the primary outcome measure; the primary end point was after completing the MBSR course. Within a 2.5-year period, 43 of the 109 randomized patients completed the mindfulness program, while 47 remained in the control g
Paul Ratanasiripong, Janet F. Park, Nop Thodsama Ratanasiripong, et al. · 2015 · Journal of Nursing Education · 157 citations
BACKGROUND: The current study investigated the efficacy of two brief intervention programs-biofeedback and mindfulness meditation-on levels of state anxiety and perceived stress in second-year Thai nursing students as they began clinical training. METHOD: Eighty-nine participants from a public nursing college in Thailand were randomly assigned to one of three groups: biofeedback group, mindfulness meditation group, or a control group. All participants were given pre- and postintervention surveys, which included demographic information; the State-Trait Anxiety Inventory (State Anxiety Scale); and the Perceived Stress Scale. RESULTS: Findings indicated that biofeedback significantly reduced an
P. Goldin, Matthew D Thurston, Santiago Allende, et al. · 2021 · JAMA psychiatry · 52 citations
Importance
Cognitive behavioral group therapy (CBGT) and mindfulness-based stress reduction (MBSR) are thought to help patients with social anxiety disorder (SAD) via distinct emotion-regulation mechanisms. However, no study has compared the effects of CBGT and MBSR on brain and negative emotion indicators of cognitive reappraisal and acceptance in patients with SAD.
Objective
To investigate the effects of CBGT and MBSR on reappraisal and acceptance in patients with SAD and to test whether treatment-associated brain changes are associated with social anxiety symptoms 1 year posttreatment.
Design, Setting, and Participants
In this randomized clinical trial, a total of 108 unmedicated adul
S. Burrowes, O. Goloubeva, Kristen Stafford, et al. · 2021 · Pain · 37 citations
Migraine patients suffer from high morbidity related to the repeated headache attacks characteristic of the disorder, poor sleep and a high prevalence of co-morbid psychosocial disorders. Current pharmacological therapies do not address these aspects of migraine, but non-pharmacological treatments such as Mindfulness Based Stress Reduction (MBSR) have been shown to improve both pain and psychological well-being. In this secondary analysis, we examined the change over time in sleep quality and psychosocial outcomes from the MRI Outcomes for Mindfulness Meditation Clinical Trial and assessed how these mediated treatment response (50% reduction in headache frequency post-intervention). We also
William Justin Morgan, Jonah Katz · 2021 · Foreign Language Annals · 36 citations
Many scholars have argued that mindfulness meditation (MM) can be beneficial in academic contexts. Recently, researchers in second language acquisition have found that higher trait mindfulness scores indicate lower foreign language classroom anxiety (FLCA). The present study investigates if mindfulness scores can be increased, if FLCA decreases as a result of a mindfulness intervention, and what opinions language learners have toward MM as a way of alleviating FLCA. Data were collected in a postsecondary learning environment where experimental group participants ( n = 76) and control group participants ( n = 66) were compared. As a result, mindfulness scores were negatively correlated with F
A. Babak, N. Motamedi, S. Mousavi, et al. · 2022 · The Journal of Tehran University Heart Center · 35 citations
Background: Hypertension is one of the most important causes of cardiovascular diseases. Patients with hypertension have a lower quality of life. We aimed to evaluate the effects of mindfulness meditation on blood pressure, mental health, and quality of life in patients with hypertension. Methods: This randomized clinical trial was performed in 2019 in Isfahan. Eighty adult women with Stage I or II hypertension were included and assigned randomly to 2 groups: 12 weeks of mindfulness-based stress reduction (MBSR) and routine care. At baseline and 1 week after the end of the intervention, blood pressure, stress, depression, anxiety, and quality of life of the studied participants were measured
Marilú Roxana Soto Vásquez, Paúl Alan Arkin Alvarado-García · 2016 · Journal of Traditional and Complementary Medicine · 34 citations
and mindfulness meditation can reduce anxiety levels in humans. A randomized experimental trial was carried out with 108 participants who were divided into 6 groups, comprising a waiting list control group and five experimental groups. Aromatherapy was carried out by inhalation of essential oils while mindfulness intervention program was focused on "flow meditation". The anxiety index was evaluated by State-Trait Anxiety Inventory (STAI). Measures were taken two times: pretest and posttest. State and Trait anxiety scores showed a decrease in posttest study phase in comparison with pretest in all experimental groups (p < 0.005), especially in those where aromatherapy and mindfulness meditatio
G. Zieff, Lee Stoner, Barnett S. Frank, et al. · 2022 · Journal of American College Health · 17 citations
Abstract This pilot study assessed the feasibility and combined effect of aerobic exercise (AE) and mindfulness meditation (MM), compared with MM alone and a control (CON) condition, on stress, anxiety, and depression in high-stress college-based young adults. Thirty-two participants (84.4% F, 20.5 ± 2.7 years, 23.9 ± 5.0 kg/m2) were randomized to a four-week, AE + MM (n = 16), MM (n = 10), or control intervention (n = 6). ANOVA revealed non-significant, but noteworthy group x time interactions (perceived stress: p = 0.09; anxiety/depression: p = 0.07). Both AE + MM and MM seem to be feasible strategies to reduce levels of stress, anxiety and depression in college-based young adults.
Orsolya Olasz, Sándor Erdős, Klára Horváth · 2024 · Mindfulness · 12 citations
The purpose of this study was to assess and compare the efficacy of different electronic devices (VR headsets and tablet devices) supported mindfulness exercises. Contrary to previous studies, we compared the technologies not only regarding psychological but also physiological parameters. Additionally, we assessed time perception as an indicator of flow state, which can increase therapeutic adherence. Fifty volunteers (26 females and 24 males) aged 19–28 years (M = 23, SD = 1.93 years) participated in our cross-over trial. A 20-min mindfulness program (Guided Meditation VR™) was shown on both a VR headset and a tablet device, with a 1-week interval in randomized order. Psychological paramete
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