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Papers on “personalized precision medicine genomics”

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  1. BMC3PM: bioinformatics multidrug combination protocol for personalized precision medicine and its application in cancer treatment

    Majid Mokhtari, Samane Khoshbakht, Mohammad Esmaeil Akbari, et al. · 2023 · BMC Medical Genomics · 7 cites

    Abstract Background In recent years, drug screening has been one of the most significant challenges in the field of personalized medicine, particularly in cancer treatment. However, several new platforms have been introduced to address this issue, providing reliable solutions for personalized drug validation and safety testing. In this study, we developed a personalized drug combination protocol as the primary input to such platforms. Methods To achieve this, we utilized data from whole-genome expression profiles of 6173 breast cancer patients, 312 healthy individuals, and 691 drugs. Our approach involved developi

  2. Advances in Personalized Medicine: Integrating Genomics and Precision Therapeutics

    Xiaoyu Qian, Jia Liao, Yu Fang · 2024 · Medicine Insights · 1 cite

    Personalized medicine represents a transformative approach to healthcare by tailoring medical treatments to individual patients based on their genetic, environmental, and lifestyle factors. This review explores the integration of genomics and precision therapeutics in personalized medicine, highlighting technological advances, applications, challenges, and future directions. Key findings include the significant impact of high-throughput sequencing, bioinformatics, artificial intelligence, and targeted therapies in improving patient outcomes. Despite existing challenges, the future of personalized medicine looks promising, with emerging technologies paving the way for more effective and indiv

  3. Good Intentions Gone Bad

    Nosheen Reza, Jessica L. Chowns, Amy Marzolf, et al. · 2019 · Circulation: Genomic and Precision Medicine

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