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Research papers on Mediterranean diet and heart health

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  2. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice

    Frank L.J. Visseren, François Mach, Yvo M. Smulders, et al. · 2021 · European Heart Journal · 6,600 citations

    The ESC Guidelines represent the views of the ESC and were produced after careful consideration of the scientific and medical knowledge and the evidence available at the time of their publication. The ESC is not responsible in the event of any contradiction, discrepancy and/or ambiguity between the ESC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to good use of healthcare or therapeutic strategies. Health professionals are encouraged to take the ESC Guidelines fully into account when exercising their clinical judgment, as well as in the determination and the implementation of preventive, diagnostic

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  3. 2016 European Guidelines on cardiovascular disease prevention in clinical practice

    Massimo Piepoli, Arno W. Hoes, Stefan Agewall, et al. · 2016 · European Heart Journal · 6,548 citations

    ABI : ankle–brachial (blood pressure) index ABPM : ambulatory blood pressure monitoring ACCORD : Action to Control Cardiovascular Risk in Diabetes ACE-I : angiotensin-converting enzyme inhibitor ACS : acute coronary syndromes ADVANCE : Action in Diabetes and Vascular disease: PreterAx

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  4. RETRACTED: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet

    Ramón Estruch, Emilio Ros, Jordi Salas‐Salvadó, et al. · 2013 · New England Journal of Medicine · 4,262 citations

    BACKGROUND: Observational cohort studies and a secondary prevention trial have shown an inverse association between adherence to the Mediterranean diet and cardiovascular risk. We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events. METHODS: In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat). Participants received quarterly individual and group educational s

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  5. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts

    Ramón Estruch, Emilio Ros, Jordi Salas‐Salvadó, et al. · 2018 · New England Journal of Medicine · 3,603 citations

    BACKGROUND: Observational cohort studies and a secondary prevention trial have shown inverse associations between adherence to the Mediterranean diet and cardiovascular risk. METHODS: In a multicenter trial in Spain, we assigned 7447 participants (55 to 80 years of age, 57% women) who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat). Participants received quarterly educational sessions and, depending on group assignment, free provision of extra-virgin olive oil, mixed nuts,

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  6. Adherence to Mediterranean diet and health status: meta-analysis

    Francesco Sofi, Francesca Cesari, Rosanna Abbate, et al. · 2008 · BMJ · 1,730 citations

    OBJECTIVE: To systematically review all the prospective cohort studies that have analysed the relation between adherence to a Mediterranean diet, mortality, and incidence of chronic diseases in a primary prevention setting. DESIGN: Meta-analysis of prospective cohort studies. DATA SOURCES: English and non-English publications in PubMed, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials from 1966 to 30 June 2008. Studies reviewed Studies that analysed prospectively the association between adherence to a Mediterranean diet, mortality, and incidence of diseases; 12 studies, with a total of 1 574,299 subjects followed for a time ranging from three to 18 years were in

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  7. Effects of a Mediterranean-Style Diet on Cardiovascular Risk Factors

    Ramón Estruch, Miguel Ángel Martínez-González, Dolores Corella, et al. · 2006 · Annals of Internal Medicine · 1,685 citations

    BACKGROUND: The Mediterranean diet has been shown to have beneficial effects on cardiovascular risk factors. OBJECTIVE: To compare the short-term effects of 2 Mediterranean diets versus those of a low-fat diet on intermediate markers of cardiovascular risk. DESIGN: Substudy of a multicenter, randomized, primary prevention trial of cardiovascular disease (Prevención con Dieta Mediterránea [PREDIMED] Study). SETTING: Primary care centers affiliated with 10 teaching hospitals. PARTICIPANTS: 772 asymptomatic persons 55 to 80 years of age at high cardiovascular risk who were recruited from October 2003 to March 2004. INTERVENTIONS: Participants were assigned to a low-fat diet (n = 257) or to 1 of

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  8. Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90.

    Ramón Estruch, Emilio Ros, Jordi Salas‐Salvadó, et al. · 2018 · New England Journal of Medicine · 1,005 citations

    To the Editor: Because of irregularities in the randomization procedures, we wish to retract the following article: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90. DOI: 10.1056/NEJMoa1200303.1 We have reanalyzed the data and have published a new report: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts. N Engl J Med. DOI: 10.1056/NEJMoa1800389.2 . . .

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  11. Mediterranean-style diet for the primary and secondary prevention of cardiovascular disease

    Karen Rees, Andrea Takeda, Nicole Martin, et al. · 2019 · Cochrane Database of Systematic Reviews · 403 citations

    BACKGROUND: The Seven Countries study in the 1960s showed that populations in the Mediterranean region experienced lower coronary heart disease (CHD) mortality probably as a result of different dietary patterns. Later observational studies have confirmed the benefits of adherence to a Mediterranean dietary pattern on cardiovascular disease (CVD) risk factors but clinical trial evidence is more limited. OBJECTIVES: To determine the effectiveness of a Mediterranean-style diet for the primary and secondary prevention of CVD. SEARCH METHODS: We searched the following electronic databases: the Cochrane Central Register of Controlled Trials (CENTRAL; 2018, Issue 9); MEDLINE (Ovid, 1946 to 25 Septe

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  12. The Mediterranean-style diet for the prevention of cardiovascular diseases

    Michel de Lorgeril, Patricia Salen · 2006 · Public Health Nutrition · 152 citations

    OBJECTIVES: To discuss present knowledge about Mediterranean diet and cardiovascular diseases. DESIGN: Review of existing literature. SETTING AND RESULTS: Epidemiological studies as well as randomised dietary trials suggest that Mediterranean diet may be important in relation to the pathogenesis (and prevention) of CHD. For instance, a striking protective effect of an ALA-rich Mediterranean diet was reported in the Lyon Diet Heart Study with a 50 to 70% reduction of the risk of recurrence after 4 years of follow-up in CHD patients. According to our current knowledge, dietary ALA should represent about 0.6 to 1% of total daily energy or about 2 g per day in patients following a Mediterranean

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  19. Impact of the Mediterranean Diet (Med-Diet) on Cancer and Cardiovascular Disease (CVD) Prevention and Management: A Narrative Review

    Ifra Chaudhary, Hassan Anwar · 2024 · International Health Review

    Cancer and cardiovascular diseases (CVD) are the leading causes of mortality and morbidity worldwide. Dietary patterns play a crucial role in the prevention and management of these life-threatening diseases. Moreover, the Mediterranean diet (Med-Diet) is consistently associated with health benefits. Therefore, the current study attempted to synthesize the contemporary scientific evidence, outlining the impact of Med-Diet on CVD. The key components of this dietary pattern include a high intake of fruits, vegetables, whole grains, seafood, olive oil, and moderate consumption of poultry and dairy products which interact to provide protective effects against these diseases. The Med-Diet  emphasi

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  20. Mediterranean Diet and Prevention of Cardiovascular Disease

    Guillermo García-Pérez-de-Sevilla, Beatriz Sánchez-Pinto Pinto · 2022 · Nutrition Today

    The adherence to the Mediterranean diet involves a relatively large intake of monounsaturated and polyunsaturated fatty acids, antioxidants, fiber, and potassium, and a low intake of saturated fat and sodium. It seems to be associated with decreased blood pressure, improved lipid profile, less inflammation, better endothelial function, and, therefore, a reduction in cardiovascular risk. To achieve these goals, the Mediterranean plan involves eating 3 servings of fish or shellfish a week, 2 servings of vegetables a day, 3 servings of fruit a day, and 90 g of nuts per week, and using olive oil as the main culinary fat. In addition, the consumption of red meat, salt, sweet and pastries, sweet b

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